A mutate is a being who acquired a physical characteristic through exposure to one or more mutagenic agents such as chemicals or radiation. Superhumans who were not born with the potential to access their innate superhuman powers are mutates.

Mutates are typically characters that have been somehow genetically mutated in order to attain their superhuman abilities, for example by exposure to magic, radiation or toxic waste, through the bite of a genetically-engineered spider, et cetera.

Human mutates are sometimes called altered human[1] or non-mutant variant.[2]

Note: Mutants that were given a Genoshan Mutate number, or used one to conceal their identity were called "Mutates".

Savage Land Mutates

The Savage Land Mutates were originally human inhabitants that were created by the mutant Magneto. They clash with the X-men and Ka-Zar on many occasions. On one occasion, they turned Spider-Man into the Man-Spider and Angel into a bird monster. They have came into conflict with the Avengers on occasions also. Although the group is fairly large they have only appeared with half of the group on each occasion they are seen. The entire group has never appeared together at one time.

Amphibius	Barbarus	Brainchild	Equilibrius	Gaza

Leash	Lorelei	Lupa	Lupo	Whiteout

Worm	Sauron Dr. Karl Lykos

Gen-Actives

Dr. Simon Tsung worked for Project: Genesis, a project run by International Operations for national defense. While there he discovered the Gen-factor, an unusual compound in the body of Ethan McCain, a reincarnation of the extra-dimensional, Sigma. Tsung left I.O. when he discovered it's leader Miles Craven had his own motive and wanted to use the Gen-Factor for military applications. Tsung's work was continued by his assistant Gabriel Newman where the Gen-Factor went through many stages of limited success and many failures, before being perfected. The Gen-Factor was successfully integrated into humans with it's 12th Generation and the Elite Operations Team, Team 7.

The powers that each Gen-Active receives, seems to be random. After exposure to the Gen Factor most of the Team 7 began to display strong telepathic and telekinetic powers as well as some healing factor. Their children however have displayed very different and unique abilities.

The telepathic link to each other is usually very weak, even unnoticeable to most. The link however is stronger between relatives and can sometimes feel when they are in extreme pain. The link also allows sensitive Gen-Actives to notice the presence of other Gen-Actives. The link is also seen making the sum of their powers greater when they are near each other.